Book a room at Days Inn - Picayune hotel near New Orleans, the perfect place to start your adventure in sunny Mississippi. Conveniently located off Interstate 59 and Highway 43, our hotel offers great value to help you get the most out of your next trip. Free parking with large-vehicle spaces makes it easy to get on and off the road. Greet the morning with free Daybreak continental breakfast with hot waffles, then return to your comfortable room, complete with free Wi-Fi Internet access, a microwave and refrigerator. Hot tub suites as well as non-smoking and handicapped-accessible rooms are available. Keep active at our indoor exercise facility and outdoor pool. Kids 17 and under stay free with an adult.