The Econo Lodge hotel in Hannibal, MO is near one mile from Hannibal-LaGrange College and near historical attractions that include Mark Twain Riverboat, Mark Twain Cave Complex, Sawyer's Creek and Mark Twain Boyhood Home and Museum. The hotel offers free breakfast, free Wi-Fi, local calls plus guest copy and fax services. All rooms come equipped with cable television. Some rooms include microwaves and refrigerators. This Econo Lodge hotel cares about the environment and has taken active steps to support green hotel practices. Whether traveling to Hannibal for business or pleasure, the Econo Lodge hotel is the perfect location for any guest. We look forward to seeing you soon. Book Now!