Convenience and comfort come standard at GuestHouse Inn & Suites Sioux Falls located off I-29 and less than a mile from the Denny Sanford Premier Center and Sioux Falls Arena & Convention Center. Offering unmatched access to a variety of nearby attractions including a bustling downtown area, Sanford Pentagon and much more. After days of exploration retreat back to our newly renovated guestrooms where you’ll be greeted by thoughtful amenities including in-room microwave, refrigerator and complimentary Wi-Fi. During your stay make use of our indoor pool, fitness facility and complimentary continental breakfast.