About Us

  • Yankton Rexall Drug, located in Yankton, SD, is proud to have served our customers for over 88 years.

    Yankton Rexall Drug is conveniently located downtown Yankton. We have many services to offer.
  • Pharmacy
    -OTC Meds
    -Prescription Delivery
    -RX refills
    -Immunizations
    -Blood Pressure checks
    -Medicare Part D Counseling

  • Gift Shop
    -Hallmark
    -Collectibles
    -Home Decor
    -Candles
    -Crystal
    -Kitchen flatware, cookware,gadgets
    -Jewelry

  • Gold Crown Hallmark Store

  • Wine & Spirits
  • Sundry Shop
    -Specialty Candy
    -Webkinz
    -candles
    -Health & Beauty Supplies
    -Souvenirs
    -Durable Medical Supplies
    -Magazines
    -Office Supplies
    -Personal Hygiene
    -Puzzles & games
  • Shipping Services
    -We are an authorized UPS shipper and drop off.
  • Bridal Registry


    Yankton Rexall has survived the many economic challenges of the last century through the determination, foresight and strong work ethic of its past owners and staff. It is the goal of the present ownership and staff to continue the tradition of providing patients and customers with quality medications and products without sacrificing the hometown customer service. You are always welcome at Yankton Rexall!