The well-being of guests is top of mind at Choice-branded hotels. Guests may experience a variety of new, improved cleanliness protocols and products. Get more of the space you need to spread out, relax or work at the pet-friendly Comfort Suites hotel in Sioux Falls, SD. Nearby destinations include University of Sioux Falls, Sioux Falls Arena, Sertoma Butterfly House, Sioux Falls Regional Airport and Great Plains Zoo and Delbridge Museum. Take advantage of amenities like free hot breakfast, free WiFi, indoor heated pool, fitness center and a 26-person meeting room. Spacious suites include a flat-screen TV, microwave, refrigerator, hair dryer and coffee maker. Also, earn rewards including free nights and gift cards with our Choice Privileges Rewards program.