Welcome to the Hampton Inn & Suites Seneca-Clemson Area, a warm and welcoming hotel just a short distance from Lake Keowee and downtown Seneca, SC. Enjoy easy access to local restaurants, state parks, lakes and leisure amenities including golf. Popular Seneca attractions including the Blue Ridge Mountains, the World of Energy and Clemson University are all close to our relaxed hotel in Seneca, SC. Settle in to a beautifully decorated guest room or suite, where you can stay connected with free WiFi at the ergonomic desk, watch the satellite TV and get a great night's sleep on the clean and fresh Hampton bed. Other great amenities include an in-room microwave and refrigerator and guest laundry facilities are available at this Seneca hotel.