The Hampton Inn & Suites - I40 Sevierville/Knoxville Tennessee hotel is located at the Foothills of the Smokey Mountains and is conveniently located between Knoxville and Gatlinburg right off I-40 Exit 407. Local attractions near this Tennessee Hampton Inn & Suites hotel include, but are not limited to, Smokey Mountain National Park, NASCAR Speed Track, shopping in Gatlinburg, Chophouse Restaurant, Five Oaks Tanger Outlet Mall and Douglas Dam. The University of Tennessee is only minutes away. We are minutes away from Dollywood Amusement Park and Aquarium, and minutes to major companies like TRW leaders in automobile industry, Home Depot and many more.