The well-being of guests is top of mind at Choice-branded hotels. Guests may experience a variety of new, improved cleanliness protocols and products. Get more for your hard-earned money at the Quality Inn Cheyenne I-25 South hotel in Cheyenne, WY near the Cheyenne Regional Airport. Other nearby sites and activities include the Terry Bison Ranch, Wyoming Hereford Ranch, Cheyenne Botanic Gardens, F. E. Warren Air Force Base and the Wyoming Territorial Prison State Historic Site. Visitors can also easily get to the Greater Cheyenne Greenway, ideal for walking, jogging or cycling. Get more value with amenities like free breakfast, fee WiFi and a free weekday newspaper. Guest rooms include TVs, refrigerators, microwaves, coffee makers, hair dryers, irons and ironing boards. Also, earn rewards including free nights and gift cards with our Choice Privileges Rewards program.