The well-being of guests is top of mind at Choice-branded hotels. Guests may experience a variety of new, improved cleanliness protocols and products. Our Quality Inn and Suites hotel has the value you are looking for when you travel. Amenities include free WiFi, free deluxe continental breakfast, a picnic area, free weekday newspapers and vending and ice machines. Spacious guest rooms feature microwaves and refrigerators, premium bedding, flat-screen TVs, coffee makers and more. Our hotel in Cayce, SC is conveniently located near the SC Statehouse, Riverbanks Botanical Garden, South Carolina State Museum, EdVenture Childrens Museum and the Columbia Museum of Art. Make the most of your time when you book a guest room at our hotel in Cayce, SC. Book a guest room today. No pets allowed.